Comparative Evaluation of the Treatment of COVID-19 with Multicriteria Decision-Making Techniques.
Identifieur interne : 000595 ( Main/Exploration ); précédent : 000594; suivant : 000596Comparative Evaluation of the Treatment of COVID-19 with Multicriteria Decision-Making Techniques.
Auteurs : Figen Sarigul Yildirim [Turquie] ; Murat Sayan [Turquie] ; Tamer Sanlidag [Turquie] ; Berna Uzun [Turquie] ; Dilber Uzun Ozsahin [Turquie] ; Ilker Ozsahin [Turquie]Source :
- Journal of healthcare engineering [ 2040-2309 ] ; 2021.
Descripteurs français
- KwdFr :
- MESH :
- administration et posologie : Antiviraux.
- méthodes : Prise de décision clinique.
- usage thérapeutique : Antiviraux.
- Humains, Logique floue, Pandémies, Techniques d'aide à la décision.
English descriptors
- KwdEn :
- MESH :
- chemical , administration & dosage : Antiviral Agents.
- chemical , therapeutic use : Antiviral Agents.
- drug therapy : COVID-19.
- methods : Clinical Decision-Making.
- Decision Support Techniques, Fuzzy Logic, Humans, Pandemics, SARS-CoV-2.
Abstract
Objectives
The outbreak of coronavirus disease 2019 (COVID-19) was first reported in December 2019. Until now, many drugs and methods have been used in the treatment of the disease. However, no effective treatment option has been found and only case-based successes have been achieved so far. This study aims to evaluate COVID-19 treatment options using multicriteria decision-making (MCDM) techniques.
Methods
In this study, we evaluated the available COVID-19 treatment options by MCDM techniques, namely, fuzzy PROMETHEE and VIKOR. These techniques are based on the evaluation and comparison of complex and multiple criteria to evaluate the most appropriate alternative. We evaluated current treatment options including favipiravir (FPV), lopinavir/ritonavir, hydroxychloroquine, interleukin-1 blocker, intravenous immunoglobulin (IVIG), and plasma exchange. The criteria used for the analysis include side effects, method of administration of the drug, cost, turnover of plasma, level of fever, age, pregnancy, and kidney function.
Results
The results showed that plasma exchange was the most preferred alternative, followed by FPV and IVIG, while hydroxychloroquine was the least favorable one. New alternatives could be considered once they are available, and weights could be assigned based on the opinions of the decision-makers (physicians/clinicians). The treatment methods that we evaluated with MCDM methods will be beneficial for both healthcare users and to rapidly end the global pandemic. The proposed method is applicable for analyzing the alternatives to the selection problem with quantitative and qualitative data. In addition, it allows the decision-maker to define the problem simply under uncertainty.
Conclusions
Fuzzy PROMETHEE and VIKOR techniques are applied in aiding decision-makers in choosing the right treatment technique for the management of COVID-19.
DOI: 10.1155/2021/8864522
PubMed: 33552457
PubMed Central: PMC7831275
Affiliations:
Links toward previous steps (curation, corpus...)
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Multicriteria Decision-Making Techniques.</title><author><name sortKey="Yildirim, Figen Sarigul" sort="Yildirim, Figen Sarigul" uniqKey="Yildirim F" first="Figen Sarigul" last="Yildirim">Figen Sarigul Yildirim</name><affiliation wicri:level="1"><nlm:affiliation>Health Science University, Antalya Education and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Antalya 07050, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Health Science University, Antalya Education and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Antalya 07050</wicri:regionArea><wicri:noRegion>Antalya 07050</wicri:noRegion></affiliation></author><author><name sortKey="Sayan, Murat" sort="Sayan, Murat" uniqKey="Sayan M" first="Murat" last="Sayan">Murat Sayan</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Medicine, Clinical Laboratory, PCR Unit, Kocaeli University, Kocaeli, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Faculty of Medicine, Clinical Laboratory, PCR Unit, Kocaeli University, Kocaeli</wicri:regionArea><wicri:noRegion>Kocaeli</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10</wicri:regionArea><wicri:noRegion>Mersin 10</wicri:noRegion></affiliation></author><author><name sortKey="Sanlidag, Tamer" sort="Sanlidag, Tamer" uniqKey="Sanlidag T" first="Tamer" last="Sanlidag">Tamer Sanlidag</name><affiliation wicri:level="1"><nlm:affiliation>DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10</wicri:regionArea><wicri:noRegion>Mersin 10</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Microbiology, Manisa Celal Bayar University, Manisa, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Medical Microbiology, Manisa Celal Bayar University, Manisa</wicri:regionArea><wicri:noRegion>Manisa</wicri:noRegion></affiliation></author><author><name sortKey="Uzun, Berna" sort="Uzun, Berna" uniqKey="Uzun B" first="Berna" last="Uzun">Berna Uzun</name><affiliation wicri:level="1"><nlm:affiliation>DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10</wicri:regionArea><wicri:noRegion>Mersin 10</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department of Mathematics, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Mathematics, Near East University, 99138 Nicosia/TRNC, Mersin 10</wicri:regionArea><wicri:noRegion>Mersin 10</wicri:noRegion></affiliation></author><author><name sortKey="Ozsahin, Dilber Uzun" sort="Ozsahin, Dilber Uzun" uniqKey="Ozsahin D" first="Dilber Uzun" last="Ozsahin">Dilber Uzun Ozsahin</name><affiliation wicri:level="1"><nlm:affiliation>DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10</wicri:regionArea><wicri:noRegion>Mersin 10</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Engineering, Faculty of Engineering, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Biomedical Engineering, Faculty of Engineering, Near East University, 99138 Nicosia/TRNC, Mersin 10</wicri:regionArea><wicri:noRegion>Mersin 10</wicri:noRegion></affiliation></author><author><name sortKey="Ozsahin, Ilker" sort="Ozsahin, Ilker" uniqKey="Ozsahin I" first="Ilker" last="Ozsahin">Ilker Ozsahin</name><affiliation wicri:level="1"><nlm:affiliation>DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10</wicri:regionArea><wicri:noRegion>Mersin 10</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Engineering, Faculty of Engineering, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Biomedical Engineering, Faculty of Engineering, Near East University, 99138 Nicosia/TRNC, Mersin 10</wicri:regionArea><wicri:noRegion>Mersin 10</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of healthcare engineering</title><idno type="eISSN">2040-2309</idno><imprint><date when="2021" type="published">2021</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antiviral Agents (administration & dosage)</term><term>Antiviral Agents (therapeutic use)</term><term>COVID-19 (drug therapy)</term><term>Clinical Decision-Making (methods)</term><term>Decision Support Techniques (MeSH)</term><term>Fuzzy Logic (MeSH)</term><term>Humans (MeSH)</term><term>Pandemics (MeSH)</term><term>SARS-CoV-2 (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Antiviraux (administration et posologie)</term><term>Antiviraux (usage thérapeutique)</term><term>Humains (MeSH)</term><term>Logique floue (MeSH)</term><term>Pandémies (MeSH)</term><term>Prise de décision clinique (méthodes)</term><term>Techniques d'aide à la décision (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Antiviral Agents</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Antiviraux</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>COVID-19</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Clinical Decision-Making</term></keywords><keywords scheme="MESH" qualifier="méthodes" xml:lang="fr"><term>Prise de décision clinique</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antiviraux</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Decision Support Techniques</term><term>Fuzzy Logic</term><term>Humans</term><term>Pandemics</term><term>SARS-CoV-2</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Humains</term><term>Logique floue</term><term>Pandémies</term><term>Techniques d'aide à la décision</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>Objectives</b></p><p>The outbreak of coronavirus disease 2019 (COVID-19) was first reported in December 2019. Until now, many drugs and methods have been used in the treatment of the disease. However, no effective treatment option has been found and only case-based successes have been achieved so far. This study aims to evaluate COVID-19 treatment options using multicriteria decision-making (MCDM) techniques.</p></div><div type="abstract" xml:lang="en"><p><b>Methods</b></p><p>In this study, we evaluated the available COVID-19 treatment options by MCDM techniques, namely, fuzzy PROMETHEE and VIKOR. These techniques are based on the evaluation and comparison of complex and multiple criteria to evaluate the most appropriate alternative. We evaluated current treatment options including favipiravir (FPV), lopinavir/ritonavir, hydroxychloroquine, interleukin-1 blocker, intravenous immunoglobulin (IVIG), and plasma exchange. The criteria used for the analysis include side effects, method of administration of the drug, cost, turnover of plasma, level of fever, age, pregnancy, and kidney function.</p></div><div type="abstract" xml:lang="en"><p><b>Results</b></p><p>The results showed that plasma exchange was the most preferred alternative, followed by FPV and IVIG, while hydroxychloroquine was the least favorable one. New alternatives could be considered once they are available, and weights could be assigned based on the opinions of the decision-makers (physicians/clinicians). The treatment methods that we evaluated with MCDM methods will be beneficial for both healthcare users and to rapidly end the global pandemic. The proposed method is applicable for analyzing the alternatives to the selection problem with quantitative and qualitative data. In addition, it allows the decision-maker to define the problem simply under uncertainty.</p></div><div type="abstract" xml:lang="en"><p><b>Conclusions</b></p><p>Fuzzy PROMETHEE and VIKOR techniques are applied in aiding decision-makers in choosing the right treatment technique for the management of COVID-19.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">33552457</PMID><DateCompleted><Year>2021</Year><Month>02</Month><Day>18</Day></DateCompleted><DateRevised><Year>2021</Year><Month>02</Month><Day>18</Day></DateRevised><Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">2040-2309</ISSN><JournalIssue CitedMedium="Internet"><Volume>2021</Volume><PubDate><Year>2021</Year></PubDate></JournalIssue><Title>Journal of healthcare engineering</Title><ISOAbbreviation>J Healthc Eng</ISOAbbreviation></Journal><ArticleTitle>Comparative Evaluation of the Treatment of COVID-19 with Multicriteria Decision-Making Techniques.</ArticleTitle><Pagination><MedlinePgn>8864522</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1155/2021/8864522</ELocationID><Abstract><AbstractText Label="Objectives">The outbreak of coronavirus disease 2019 (COVID-19) was first reported in December 2019. Until now, many drugs and methods have been used in the treatment of the disease. However, no effective treatment option has been found and only case-based successes have been achieved so far. This study aims to evaluate COVID-19 treatment options using multicriteria decision-making (MCDM) techniques.</AbstractText><AbstractText Label="Methods">In this study, we evaluated the available COVID-19 treatment options by MCDM techniques, namely, fuzzy PROMETHEE and VIKOR. These techniques are based on the evaluation and comparison of complex and multiple criteria to evaluate the most appropriate alternative. We evaluated current treatment options including favipiravir (FPV), lopinavir/ritonavir, hydroxychloroquine, interleukin-1 blocker, intravenous immunoglobulin (IVIG), and plasma exchange. The criteria used for the analysis include side effects, method of administration of the drug, cost, turnover of plasma, level of fever, age, pregnancy, and kidney function.</AbstractText><AbstractText Label="Results">The results showed that plasma exchange was the most preferred alternative, followed by FPV and IVIG, while hydroxychloroquine was the least favorable one. New alternatives could be considered once they are available, and weights could be assigned based on the opinions of the decision-makers (physicians/clinicians). The treatment methods that we evaluated with MCDM methods will be beneficial for both healthcare users and to rapidly end the global pandemic. The proposed method is applicable for analyzing the alternatives to the selection problem with quantitative and qualitative data. In addition, it allows the decision-maker to define the problem simply under uncertainty.</AbstractText><AbstractText Label="Conclusions">Fuzzy PROMETHEE and VIKOR techniques are applied in aiding decision-makers in choosing the right treatment technique for the management of COVID-19.</AbstractText><CopyrightInformation>Copyright © 2021 Figen Sarigul Yildirim et al.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Yildirim</LastName><ForeName>Figen Sarigul</ForeName><Initials>FS</Initials><Identifier Source="ORCID">0000-0001-8646-2203</Identifier><AffiliationInfo><Affiliation>Health Science University, Antalya Education and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Antalya 07050, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sayan</LastName><ForeName>Murat</ForeName><Initials>M</Initials><Identifier Source="ORCID">0000-0002-4374-7193</Identifier><AffiliationInfo><Affiliation>Faculty of Medicine, Clinical Laboratory, PCR Unit, Kocaeli University, Kocaeli, Turkey.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sanlidag</LastName><ForeName>Tamer</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Medical Microbiology, Manisa Celal Bayar University, Manisa, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Uzun</LastName><ForeName>Berna</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Mathematics, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ozsahin</LastName><ForeName>Dilber Uzun</ForeName><Initials>DU</Initials><Identifier Source="ORCID">0000-0002-3873-1410</Identifier><AffiliationInfo><Affiliation>DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Biomedical Engineering, Faculty of Engineering, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ozsahin</LastName><ForeName>Ilker</ForeName><Initials>I</Initials><Identifier Source="ORCID">0000-0002-3141-6805</Identifier><AffiliationInfo><Affiliation>DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Biomedical Engineering, Faculty of Engineering, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2021</Year><Month>01</Month><Day>22</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Healthc Eng</MedlineTA><NlmUniqueID>101528166</NlmUniqueID><ISSNLinking>2040-2295</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000998">Antiviral Agents</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000998" MajorTopicYN="N">Antiviral Agents</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000086382" MajorTopicYN="N">COVID-19</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000066491" MajorTopicYN="N">Clinical Decision-Making</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003661" MajorTopicYN="Y">Decision Support Techniques</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017143" MajorTopicYN="Y">Fuzzy Logic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000086402" MajorTopicYN="N">SARS-CoV-2</DescriptorName></MeshHeading></MeshHeadingList><CoiStatement>The authors declare no conflicts of interest.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>08</Month><Day>28</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2020</Year><Month>12</Month><Day>25</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2021</Year><Month>01</Month><Day>09</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2021</Year><Month>2</Month><Day>8</Day><Hour>5</Hour><Minute>37</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2021</Year><Month>2</Month><Day>9</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2021</Year><Month>2</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId 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